COVID-19 vaccine update: Some doses kept too cold, Pfizer having manufacturing issues, US officials say

Covid-19-Vaccine-development

The first days of Pfizer Inc’s COVID-19 vaccine rollout have seen unexpected hitches including some vaccines being stored at excessively cold temperatures and Pfizer reporting potential challenges in its vaccine production, US officials said on a Wednesday press call.

At least two trays of COVID-19 vaccine doses delivered in California needed to be replaced after their storage temperatures dipped below minus 80 Celsius (minus 112 Fahrenheit), US Army General Gustave Perna said on the call. Pfizer’s vaccines, made with partner BioNTech SE, are supposed to be kept at around minus 70C.

Officials are investigating whether storing the vaccines at excessively cold temperatures poses a safety or efficacy risk, he said.

Pfizer also has reported some production issues, US Secretary of Health and Human Services Alex Azar said.

We will ensure that by whatever mechanism, that we provide them full support to ensure that they can produce for the American people

Pfizer did not immediately respond to a request for comment, but its Chief Executive Albert Bourla told CNBC earlier this week the company was asking the US government to use the Defense Production Act to relieve some “critical supply limitations,” particularly in some components. He did not provide further details.

Officials did not outline what the specific manufacturing challenges were.

Ugur Sahin, chief executive of Pfizer’s partner BioNTech, told Reuters last week that Pfizer’s initial 2020 production target of 100 million doses was halved earlier this year in part over issues with raw materials supply. He said that has since been resolved and manufacturing has begun at scale.

Officials said Wednesday they plan to allocate 2 million doses of the Pfizer vaccine next week and 5.9 million doses of Moderna Inc’s, assuming it receives regulatory authorization. Moderna’s vaccine is likely to be authorized as soon as Friday, they said.

The US government is in talks with Pfizer to secure 100 million additional doses, US Operation Warp Speed chief adviser Dr. Moncef Slaoui said on the call. It had previously contracted with Pfizer for the option to buy up to 500 million additional doses at an unspecified price.

Officials said on Wednesday the United States has already contracted for 300 million vaccine doses between the Pfizer/BioNTech shot and one from Moderna in the first half of next year, and 900 million doses in total from drugmakers developing COVID-19 vaccines.

Officials said logistics companies United Parcel Services Inc and FedEx Corp are developing contingency plans for vaccine deliveries this week in response to forecasts of severe snowstorms in some parts of the United States.

Source: https://www.moneycontrol.com/news/coronavirus/covid-19-vaccine-update-some-doses-kept-too-cold-pfizer-having-manufacturing-issues-us-officials-say-6236691.html

RSS Latest Press Release

  • The Mold Girl Ramps Up Annual Air Quality Testing Following High Demand
    Daniel Island, SC – Entrepreneur Elizabeth Keefer, aka The Mold Girl, is stepping up to meet demand from worried residents concerned about their homes being afflicted with significant health hazards.   Keefer, a well-respected council-certified indoor environmental professional, is now offering annual air quality testing for homeowners worried their homes could have mold, allergens, or other […]
  • Wendy's and Google Cloud partner to enhance the Wendy's restaurant experience
    Wendy's®  and Google Cloud today announced a partnership to enhance Wendy's restaurant experience and unlock new customer, restaurant, and employee experiences through data-driven insights.Wendy's intends to leverage Google Cloud's data analytics, artificial intelligence (AI), machine learning (ML), and hybrid cloud tools to create new ways customers can order food in the drive-thru, on their mobile […]
  • Unique Custom Marine Vault Launches New Storage Boating Facility
    Pompano Beach, FL: A new 25,000 sqft boat storage warehouse has opened to offer the best complete boat care service in Florida’s Pompano Beach.   Owned and operated by Unique Custom Marine Vault, the unit is a safe and secure marine facility with an in-house mechanic and boat transporters.    “If you are looking for a […]
  • Dreamstime launches the "Cover of the Year 2021 in Romania" contest with prizes totaling 7,500 Euros.
    Dreamstime, the world’s largest stock photo community, together with Cărturești and PressOne, announces the launch of the "Cover of the Year 2021 in Romania" contest for book cover illustrations. Publishers or graphic artists who have published books with original covers throughout 2020 and 2021 are invited to participate. Participants can submit covers using stock media […]